So do you think CBDA will be the next trend in natural health? Quite possibly!
CBDA is the precursor to CBD. According to Leafly, “CBDA (cannabidiolic acid) is one of many compounds produced by cannabis and hemp. Abundant in the live plants of CBD varieties, it converts to the better known cannabinoid CBD (cannabidiol) over time and when exposed to heat.”
Here are some points to help you understand CBDA further:
- Scientists learned in 2018 that CBDA may have the potential to help treat depression. In a rat study, CBDA helped with lessening stress- and anxiety-driven behavior.
- CBDA has shown to be more effective than CBD in treating nausea. In a study with rats, “CBDA appears to be able to reduce emetic attacks and simultaneously increase the latency of the emesis onset in rats in response to movement with a more powerful effect than CBD,” says an article in the journal Molecules.
- Like THC and CBD, CBDA impacts the endocannabinoid system. But it does not attach onto CB1 and CB2 receptors. “Instead, CBDA interacts with the endocannabinoid system by inhibiting the cyclooxygenase-2 (COX-2) enzyme. COX-2 enzymes are associated with inflammation after an injury or infection, so by blocking COX-2 enzymes, CBDA can relieve inflammation and associated pain,” explains Leafly.
Truly, the hemp and cannabis plant have so much to offer us in terms of pain- and anxiety-relief. Do you have anymore questions about CBDA, hemp or cannabis? Click here to contact us in Streetsville, Mississauga. Talk to you soon!
Bolognini D, Rock EM, Cluny NL, et al. Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation. Br J Pharmacol. 2013;168(6):1456-1470. doi:10.1111/bph.12043
Formato M, Crescente G, Scognamiglio M, et al. (‒)-Cannabidiolic Acid, a Still Overlooked Bioactive Compound: An Introductory Review and Preliminary Research. Molecules. 2020;25(11):2638. Published 2020 Jun 5. doi:10.3390/molecules25112638
Hen-Shoval D, Amar S, Shbiro L, Smoum R, Haj CG, Mechoulam R, Zalsman G, Weller A, Shoval G. Acute oral cannabidiolic acid methyl ester reduces depression-like behavior in two genetic animal models of depression. Behav Brain Res. 2018 Oct 1;351:1-3. doi: 10.1016/j.bbr.2018.05.027. Epub 2018 May 31. PMID: 29860002.