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Did you know that THC and CBD are cannabinoids? Contact us if you want to learn more from our educators.

It’s not uncommon for people to talk about cannabis and hemp, and then casually slip in the word “cannabinoids”.

So what the heck are cannabinoids?

In simple terms, cannabinoids are molecules from both the hemp and cannabis plants. According to Discover Magazine, “Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors in the body. …Cannabinoids interact with cannabinoid receptors to regulate a variety of functions in the body, such as inflammation, pain perception, mood, and memory. They can also be used to treat a variety of medical conditions.”

Cannabinoids include THC, CBD, CBN and CBG, as well as other lesser-known molecules such as CBC and CBDA. The cannabis plant alone contains over 480 components, and about 66 of them are considered to be official cannabinoids.

As you might already be aware, each of these components have therapeutic properties. What’s more, when each cannabinoid is combined with other cannabinoids, they can provide an “entourage effect.” In other words, when cannabinoids are taken together, they could provide further healing effects. For example, according to a study conducted in 2010, “…patients with cancer pain were given either a pure THC extract or an extract containing near-equal levels of both THC and CBD—patients given the THC/CBD combo reported having less pain,” explains Leafly.

If you want to reap the benefits of the entourage effect, please speak to a Canna Relief educator. We can also connect you with a medical doctor if you’re inquiring about a medical cannabis prescription. Call us at 905-284, 4420 or click here to send us a message.

References:

https://www.discovermagazine.com/lifestyle/what-are-cannabinoids-their-benefits-side-effects-and-more

http://files.iowamedicalmarijuana.org/petition/2012/Johnson_2010.pdf

https://www.leafly.ca/news/cannabis-101/cannabis-entourage-effect-why-thc-and-cbd-only-medicines-arent-g

https://www.cnn.com/2014/03/11/health/gupta-marijuana-entourage/index.html

Need help understanding CBD, THC, and other cannabinoids? We’re here to help! Call our educators at 905-286-4420.

If you follow natural health trends, you’ve likely heard that CBN and CBG are the next big things from hemp and cannabis plants.

So do you think CBDA will be the next trend in natural health? Quite possibly!

CBDA is the precursor to CBD. According to Leafly, “CBDA (cannabidiolic acid) is one of many compounds produced by cannabis and hemp. Abundant in the live plants of CBD varieties, it converts to the better known cannabinoid CBD (cannabidiol) over time and when exposed to heat.”

Here are some points to help you understand CBDA further:

Scientists learned in 2018 that CBDA may have the potential to help treat depression. In a rat study, CBDA helped with lessening stress- and anxiety-driven behavior.
CBDA has shown to be more effective than CBD in treating nausea. In a study with rats, “CBDA appears to be able to reduce emetic attacks and simultaneously increase the latency of the emesis onset in rats in response to movement with a more powerful effect than CBD,” says an article in the journal Molecules.
Like THC and CBD, CBDA impacts the endocannabinoid system. But it does not attach onto CB1 and CB2 receptors. “Instead, CBDA interacts with the endocannabinoid system by inhibiting the cyclooxygenase-2 (COX-2) enzyme. COX-2 enzymes are associated with inflammation after an injury or infection, so by blocking COX-2 enzymes, CBDA can relieve inflammation and associated pain,” explains Leafly.

Truly, the hemp and cannabis plant have so much to offer us in terms of pain- and anxiety-relief. Do you have anymore questions about CBDA, hemp or cannabis? Click here to contact us in Streetsville, Mississauga. Talk to you soon!

References

https://www.leafly.ca/news/cbd/what-is-cbda-cannabidiolic-acid-marijuana-cannabinoid

Bolognini D, Rock EM, Cluny NL, et al. Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation. Br J Pharmacol. 2013;168(6):1456-1470. doi:10.1111/bph.12043

Formato M, Crescente G, Scognamiglio M, et al. (‒)-Cannabidiolic Acid, a Still Overlooked Bioactive Compound: An Introductory Review and Preliminary Research. Molecules. 2020;25(11):2638. Published 2020 Jun 5. doi:10.3390/molecules25112638

Hen-Shoval D, Amar S, Shbiro L, Smoum R, Haj CG, Mechoulam R, Zalsman G, Weller A, Shoval G. Acute oral cannabidiolic acid methyl ester reduces depression-like behavior in two genetic animal models of depression. Behav Brain Res. 2018 Oct 1;351:1-3. doi: 10.1016/j.bbr.2018.05.027. Epub 2018 May 31. PMID: 29860002.

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